Job Description

Job Description

Job Description

Role: Analytical Chemist

Location: San Francisco, CA

Pay: $110-160,000

Responsibilities:

1. Design and execute experiments to fully characterize the oligonucleotide drug substance and drug product materials.
2. Demonstrate proficiency with analytical characterization techniques (e.g., mass spectrometry, liquid chromatography, UV/Fluorescence, and electrophoresis)
3. Ability to independently conceive, develop, execute, and then implement novel/advanced scientific techniques. Holistic thinker for analytical packages.
4. Report at project team meetings, write analytical development reports, provide recommendations to management.
5. Manage and support junior team members.
6. Collaborate with internal and external manufacturing partners to develop robust analytical methods.
7. Participate in multidisciplinary teams including Biology (in vitro and in vivo pharmacology), and Chemistry (production, analytical sciences, and platform chemistry groups) – Present results through team meetings and recommendations to management.
8. Deliver innovative solutions using a diversity of thought and experiences.
9. Ensure the quality of each delivered entity.
10. Maintain lab notebooks, report data with analysis of results in presentations and/or written reports to the scientific team.

Required Qualifications

1. The level of this position will depend on education and experience qualifications:
2. Scientist – PhD in analytical, organic chemistry or a related discipline with minimum of 4 years of direct experience in oligonucleotide analysis and formulation
3. Scientist – PhD in analytical, organic chemistry or a related discipline with minimum of 1 year of direct experience in oligonucleotide analysis and formulation
4. Principal Research Associate – MS in analytical, organic chemistry or a related discipline with minimum of 8 years of direct experience in oligonucleotide analysis and formulation
5. Experience in the biotechnology and/or pharmaceutical industry is preferred, with direct experience with (semi)automated instruments.
6. Strong method development skills including experience with liquid chromatography, capillary electrophoresis and mass spectrometry techniques.
7. Proficiency with Chromeleon, Xcalibur and Biopharma Finder is preferred.
8. Experience with managing project teams in a biotechnology organization is preferred.
9. A history of authoring publications and/or study reports.
10. A deep commitment to working as part of teams to deliver breakthrough medicines.
11. Excellent communication, organization, and time management skills and ability to work both independently and collaboratively.

IND 005-010

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